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. Author manuscript; available in PMC: 2015 May 21.
Published in final edited form as: Mol Cell Biochem. 2009 Jul 9;332(0):173–181. doi: 10.1007/s11010-009-0188-0

Figure 5. The NLS recognized in PRH by Kap7 most likely includes the basic residues at the C-terminal of the homeodomain.

Figure 5

A. PRH and Caudal, which share similar import pathways via Kap7, share high similarity within the domain responsible for binding to Kap7. The homeodomain regions of PRH and Caudal (dashed lines) are aligned. The thick bars represent α helical regions. Residues highlighted in gray are similar between PRH and Caudal. The underlined region of Caudal confers binding to Kap7 (48). Conserved basic residues within this region are marked by dark gray.