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IRAK-1 is required for LPS-mediated suppression of GPX3 and catalase. The message levels of GPX3 and catalase from liver and kidney tissues of WT and IRAK-1 deficient mice injected with either PBS or LPS were measured by real-time RTPCR. Each data point represents the mean ± SD (N = 4) of at least three independent experiments. *P < 0.05.
