Figure 1. Localization of ERα in LCC1 and LCC9 cells treated with fulvestrant.
LCC1 (A) and LCC9 (B) breast cancer cells were treated with 500 nM ICI for 24 hours. Confocal microscopy indicates localization of the ERα (red) and nucleus (blue). These data give background on ER localization and indicate possible mechanism of ICI stimulating UPR signaling which was shown in Cook et al. 2014 [2].