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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Medchemcomm. 2014 Dec 16;6(4):613–618. doi: 10.1039/C4MD00401A

Table 1.

Selected HDAC % inhibition data for compounds 9-24.a

graphic file with name nihms-653753-f0004.jpg
R HUAC 1 HUAC 2 HUAC 6 HDAC 10
9 graphic file with name nihms-653753-t0005.jpg 63 30 50 49
10 graphic file with name nihms-653753-t0006.jpg 61 54 62 47
11 graphic file with name nihms-653753-t0007.jpg 44 35 49 36
12 graphic file with name nihms-653753-t0008.jpg 36 29 48 70
13 graphic file with name nihms-653753-t0009.jpg 62 32 46 59
14 graphic file with name nihms-653753-t0010.jpg 61 52 48 49
15 graphic file with name nihms-653753-t0011.jpg 48 45 40 45
16 graphic file with name nihms-653753-t0012.jpg 42 36 31 45
17 graphic file with name nihms-653753-t0013.jpg 35 25 46 32
18 graphic file with name nihms-653753-t0014.jpg 27 0 27 57
19 graphic file with name nihms-653753-t0015.jpg 43 1 50 91
10 graphic file with name nihms-653753-t0016.jpg 32 19 21 76
21 graphic file with name nihms-653753-t0017.jpg -- -- -- --
22 graphic file with name nihms-653753-t0018.jpg 70 57 60 47
23 graphic file with name nihms-653753-t0019.jpg 47 41 31 56
24 graphic file with name nihms-653753-t0020.jpg 26 32 60 55
a

Data shown was determined at a 20 μM concentration of each compound. Data points are the average of 3 determinations that in each case differed by 5% or less. Compound 21 was insoluble.