Table 1. Plasma Insulin, FFA, Leptin, and HOMA-IR Measurements.

	Fed		Fasted
Group	Insulin (ng/mL)		Insulin (ng/mL)		FFA (mmol/L)		Leptin (ng/mL)		HOMA-IR
	10 weeks	16 weeks	10 weeks	16 weeks	10 weeks	16 weeks	10 weeks	16 weeks	10 weeks	16 weeks
ZL	1.94±0.30	3.15±0.94	1.69±0.41	1.55±0.41	0.08±0.02	0.06±0.01	2.55±1.1	5.28±0.55	11.6±3.7	10.6±2.8
ZDF	6.89±1.2*	2.57±0.42	3.94±1.4*	1.88±0.68*	0.34±0.12*	0.29±0.02*	30.7±2.7*	25.1±9.0*	36.7±11*	42.8±24*

FFA: free fatty acids; HOMA-IR: homeostatic model of insulin resistance; Insulin was measured in the fed and fasted states, FFA and Leptin were measured in the fasted state only. HOMA-IR was calculated from fasted glucose and insulin. Data are mean ± SD

*p<0.05 to ZL, Student's t-test; n = 3 in fed state and n = 4–7 in fasted state per group.