Fig 8. Biodistribution of hydrogel nanoparticles in the alimentary tract of Anopheles gambiae females following a 1 day oral challenge.

Following oral challenge with the respective NPs (250 μg/mL), fluorescence signal was detected in all alimentary tract tissues, including Ventral diverticulum (VD), dorsal diverticulum (DD), foregut (FG), midgut (MG) and cardia (arrow). Fluorescence was not detected in the alimentary tracts of the control, sucrose-fed females. Bright field micrographs show the outline of the tissues from control mosquitoes that were not challenged with NPs. Bar = 1 μm