Fig 13. Biodistribution of 80 nm x 320 nm hydrogel nanoparticles in the alimentary tracts of Anopheles gambiae females 1 d following contact challenge.

Female mosquitoes were challenged by administration of NPs to the head. (A) Negatively charged NPs. (B) Positively charged NPs. (C) Control mosquitoes. Negatively charged NPs trafficked more effectively and were detected more frequently and abundantly in alimentary tract tissues and the proboscis than positively charged NPs. VD = ventral diverticulum; DD = dorsal diverticula; FG = foregut; Bar = 1 μm