Table 4. Comparison of in-vitro and in-vivo application of NAC (1 x SC = 15mg NAC/ml blood) at different time-points prior to and post irradiation (n = 10, repeated 3 times for each volunteer).

	w/o anti-oxidant	4h before	3h before	2h before	1h before	30 min before	15min before	After radiation
in-vitro	0.147 ± 0.020	0.130 ± 0.008	0.118 ± 0.017*	0.115 ± 0.014*	0.097 ± 0.017*	0.096 ± 0.016*	0.130 ± 0.007*	0.155 ± 0.017
in-vivo	0.152 ± 0.010	0.075 ± 0.018*	0.065 ± 0.017*	0.070 ± 0.021*	0.062 ± 0.014*	0.073 ± 0.010*	0.103 ± 0.018*	0.150 ± 0.009

The numbers indicate mean values and standard deviations of excess foci/cell after 10 mGy irradiation.

* indicates a significant deviation from the initial level (p <0.05) using Dunnett's test.