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. 2015 May 21;10(5):e0127811. doi: 10.1371/journal.pone.0127811

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© 2015 Pingel et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 1 — mRNA levels of the inflammatory markers TNF-α, IL-1R1, IL-6, IL-10 and MCP1 and of the macrophage marker CD68 were significantly elevated in the Kager’s fat pad of AT patients (n = 30) compared to healthy CON subjects (n = 13). The expression of target gene mRNA was normalized to the expression of TBP mRNA. Normalized mRNA expression for the control subjects was set to 1. * p < 0.05 (compared to CON). TNF-α, tumor necrosis factor-α; IL-1R1, interleukin-1 receptor 1; IL-6, interleukin-6; IL-10, interleukin-10; MCP1, monocyte chemotactant protein-1; CD68, cluster of differentiation 68; CON, control; AT, Achilles tendinopathy; TBP, TATA-binding protein.