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Size and surface charge of DOX-encapsulated PLGA NPs, formulated with 0.25 % w/v PVA as the surfactant/stabilizer. (n = 6, mean ± S.D).
| Blank NPs | DOX loading [%; w/w ratio to PLGA] | ||
|---|---|---|---|
| Agent-free | 2 | 5 | |
| Size [nm] | 386.8 ± 46.5 | 343.8 ± 5.3 | 342.3 ± 1.4 |
| ζ-potential [mV] | -30.3 ± 2.3 | -28.2 ± 1.0 | -31.6 ± 1.0 |
| Encapsulation efficiency [%] | N/A | 58.3 ± 0.5 | 57.9 ± 0.9 |
