Fig. 5.

Demonstration of the use of finger opposition as a functional localiser in brainstem fMRI at 3 T and at 7 T, by imaging activation in the ipsilateral cuneate nucleus of the medulla (z -54). The 3 T data is derived from previously-published results (Pattinson et al., 2009a). This technique provides confidence in the analysis model and registration accuracy of the current 7 T study. The images consist of a colour-rendered statistical map superimposed on a standard (MNI 1 mm³) brain. Significant regions are displayed with a threshold Z > 2.3, with a cluster probability threshold of p < 0.05 (corrected for multiple comparisons). The sagittal image on the right displays the position of slices, for clarity only displayed from the 7 T acquisition. Abbreviations: R, raphe nuclei; ret, nuclei reticularis; VII, facial nucleus; Amb, nucleus ambiguous; IX, glossopharyngeal nucleus; NTS, nucleus tractus solitaries; GC, gracile (medial) and cuneate (lateral) nuclei (in blue). R (right) and L (left) indicate image orientation. Original line drawings adapted from Duvernoy (1995).