Table 2.

List of drugs under trials

Type	Investigational Drug	Intended Actions	Clinical trial phase	Dosage form	References
Erythematotelangiectatic rosacea	Laropiprant	Human prostaglandin D2 receptor-1	Early phase	Topical	52
			(On hold)
	Aganirsen	Antisense oligonucleotide	Early phase	Topical	53
Papulopustular rosacea	Omiganan pentahydrochloride	Disruption of the cytoplasmic membranes	Phase III	Topical	60, 61
	Ivermectin 1% cream	-n/a-	Phase III completed	Topical	55
	Carbamide peroxide	Inhibiting inflammatory mediators	Phase III completed	Topical	62
	SGT-VD-54	-n/a-	Phase II	Topical	62
	Sarecycline hydrochloride	Down regulates inflammatory cytokine production	Phase II	Oral	63
	Apremilast	Modulates multiple anti-inflammatory pathways	Phase II completed	Oral	56
	Azelaic acid foam		Phase III ongoing	Topical Author et. al	57
	Incobotulinumtoxin A	-n/a-	Phase II	I.V	58, 64
Phymatous Rosacea	No specific drug under trials	-n/a
Ocular Rosacea	No specific drug under trials	-n/a-

-n/a- = Not available; I.V= Intravenous.