Table 4.
Analysis of mean SGN number at each level of the cochlea for each treated time point cohort. The significant variation in the mid-turn counts results from SGN losses at later stages, being evident at 10wk and more noticeable at 20wk post-treatment. ‘n’ refers to the number of animals counted per condition.
| Apical |
Mid |
Basal |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Cells/mm2 | n | p < 0.05? | Cells/mm2 | n | p < 0.05? | Cells/mm2 | n | p < 0.05? | |
| Untreated | 1839 | 5 | n/a | 2106 | 5 | n/a | 2168 | 5 | n/a |
| 1wk | 1834 | 3 | No | 2016 | 3 | No | 2156 | 3 | No |
| 10–20wk | 1870 | 5 | No | 1857 | 5 | Yes* | 2104 | 5 | No |
| 20wk+ | 1802 | 4 | No | 1730 | 4 | Yes** | 2132 | 4 | No |