Table 3. Differential expression level of key immunological genes following Probioglat stimulation compared with GA at 6h. Shown are p-values for qPCR results from single-tailed t-tests with unequal variance, and FDR-adjusted p-values from LIMMA comparisons.
Genes |
CCL5 |
CD9 |
CXCL10 |
MMP1 |
MMP9 |
|||||
---|---|---|---|---|---|---|---|---|---|---|
Method | FC | p value | FC | p value | FC | p value | FC | p value | FC | p value |
qPCR | 1.12 | 4.05E-05 | 1.11 | 0.0004 | 2.28 | 0.0029 | 1.25 | 0.0201 | 1.24 | 0.0168 |
FDR-adjusted Microarray | 1.09 | 0.02 | 1.15 | 0.002 | 1.46 | 0.0006 | 1.5 | 0.002 | 1.29 | 2.80E-06 |
FC: fold change; qPCR: quantitative RT-PCR; FDR: For the microarray data, since all probesets on the microarray were tested, p values were adjusted using FDR for testing multiple hypotheses.