Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
FK-3000 reduced NF-κB phosphorylation levels and COX-2 expression. In MDA-MB-231 cells treated with 5.0 μg/ml FK-3000 for 120 min, NF-κB phosphorylation decreased to nearly undetectable levels compared with the 0.5 μg/ml treated cells at 120 min or the 5.0 μg/ml treated cells at 60–90 min. FK-3000 suppressed COX-2 protein expression in a dose- and time-dependent manner.
