Table II.
Complete blood cell counts from MDA-MB-231 xenografted mice in the treatment and control groups.
| Control | Taxol | FK-3000 | FK-3000+Taxol | |
|---|---|---|---|---|
| Leukocytes | ||||
| WBC (k/μl) | 3.39±2.54 | 7.12±3.17 | 5.06±2.56 | 3.93±1.47 |
| NE (k/μl) | 1.12±0.78 | 2.24±1.05 | 1.99±1.11 | 1.55±0.95 |
| LY (k/μl) | 1.89±1.55 | 4.03±1.76 | 2.41±1.29 | 2.01±0.45 |
| MO (k/μl) | 0.17±0.13 | 0.42±0.18 | 0.29±0.12 | 0.20±0.07 |
| EO (k/μl) | 0.16±0.13 | 0.33±0.18 | 0.29±0.13 | 0.15±0.10 |
| BA (k/μl) | 0.05±0.03 | 0.10±0.05 | 0.09±0.05 | 0.05±0.05 |
| Erythrocytes | ||||
| RBC (M/μl) | 9.36±0.41 | 9.47±0.42 | 9.53±1.16 | 9.57±0.31 |
| Hb (M/dl) | 12.76±0.42 | 13.14±0.49 | 10.80±5.13 | 13.30±0.63 |
| HCT (%) | 49.84±2.22 | 50.16±1.36 | 50.86±4.94 | 52.00±1.52 |
| MCV (fl) | 53.26±0.91 | 53.54±1.76 | 53.54±1.76 | 54.34±1.69 |
| MCH (pg) | 13.66±0.49 | 13.56±1.31 | 13.56±1.31 | 13.88±0.51 |
| MCHC (g/dl) | 25.62±0.76 | 25.26±1.71 | 25.26±1.71 | 25.58±0.91 |
| RDW (%) | 16.46±0.43 | 17.42±2.30 | 16.88±1.70 | 16.80±0.25 |
| Thrombocyte | ||||
| PLT (k/μl) | 521.8±142.7 | 392.6±57.36 | 234.8±73.58 | 435.0±166.2 |
| MPV (fl) | 4.74±0.17 | 5.10±0.60 | 5.36±0.60 | 4.92±0.40 |
Each group was administered vehicle (0.1% DMSO), Taxol (10 mg/kg body weight/week), FK-3000 (1 mg/kg body weight/day), or both Taxol and FK-3000. There was no difference in the blood cell counts between the groups.