Table III.
Complete blood chemistry from MDA-MB-231 xenografted mice in the treatment and control groups.
| Control | Taxol | FK-3000 | FK-3000+Taxol | |
|---|---|---|---|---|
| GOT (U/I) | 72.2±10.63a | 63.60±3.71 | 65.20±3.77 | 64.40±4.50 |
| GPT (U/I) | 25.00±2.55a | 30.20±5.20 | 25.80±2.17 | 24.60±2.61 |
| BUN (mg/dl) | 42.84±9.47a | 36.50±4.45 | 52.00±6.32 | 59.30±11.58 |
| NH3 (μg/dl) | 95.4±3.51a | 97.80±5.07 | 92.00±1.41 | 97.40±3.78 |
| TBIL (mg/dl) | 0.36±0.15a | 0.38±0.13 | 0.44±0.09 | 0.43±0.18 |
| ALB (g/dl) | 2.34±0.15a | 2.32±0.22 | 2.46±0.15 | 2.42±0.13 |
Each group was administered vehicle (0.1% DMSO), Taxol (10 mg/kg body weight/week), FK-3000 (1 mg/kg body weight/day), or both Taxol and FK-3000.
a
The differences are statistically not significant between each group.