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. 2015 Apr 20;46(6):2327–2334. doi: 10.3892/ijo.2015.2974

Figure 2.

Figure 2

Comparison of dThd, FTD and FdUrd incorporation (A) into DNA and elimination of dThd and FTD (B) from DNA after a washout step. (A) HCT116 cells were treated for 1, 2, 4, 10 or 24 h with each compound at 1 μmol/l, and DNA incorporation was measured by LSC. (B) Following 24-h treatment with dThd or FTD, these compounds were washed out. At 24, 48 and 72 h following the washout step, the amount of dThd or FTD remaining incorporated into DNA was measured by liquid scintillation counting. Open circles, triangles and squares represent the incorporation of dThd, FTD and FdUrd, respectively.