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. 2015 Apr 1;46(6):2629–2638. doi: 10.3892/ijo.2015.2946

Figure 4.

Figure 4

Nobiletin induces a concentration-dependent decrease of VEGF production from human ovarian cancer cells. The human ovarian cancer cell line OVCAR-3 (A), and A2780/CP70 (B) were treated with varying concentrations of nobiletin for 16 h. Subsequently, the VEGF levels in the supernatant was measured by ELISA. A total of three independent experiments, each in triplicates, were assayed, and the mean VEGF protein level from each duplicate was used for statistical analysis. *P<0.05 as compared to control. **P<0.01 as compared to control.