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. Author manuscript; available in PMC: 2015 May 22.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2009 Sep 29;18(10):2694–2700. doi: 10.1158/1055-9965.EPI-08-0821

FIGURE 2.

FIGURE 2

The analysis of multiple breast lesions from patient BP18 displays heterogeneity in APC, CDH1 and CTNNB1. Slide BP18-6 shows a DCIS (A) and an IDC (B), BP18-9 displays two DCIS (A and B) and BP18-7 an IDC. The target gene/ACTB ratio for APC, CDH1 and CTNNB1 are indicated for each of the genes. APC methylation is present in all the lesions with ratios above the cut off of 20.73; CDH1 methylation was above the cut-off of 8.10 only in BP18-9 and CTNNB1 methylation levels were above the cut-off of 2.65 for BP18-9B and BP18-7