Table 3. The estimate differences in scores between the no migraine group and the migraine groups at the two-year follow-up. a . b , c , d .
| Undertreated group | Treated group | |||
|---|---|---|---|---|
| Inactive migraine vs. No migraine | Active migraine vs. No migraine | Inactive migraine vs. No migraine | Active migraine vs. No migraine | |
| HAMD | 2.39 | 8.93** | -2.59 | 5.60 |
| DS | 1.35 | 8.01* | -3.34 | 2.07 |
| SS | 1.04 | 14.61** | -0.54 | 3.12 |
| HADS-D | 1.20 | 3.70 | -1.58 | -1.19 |
| HADS-A | 0.64 | 6.06** | 0.09 | 1.85 |
HAMD = Hamilton Depression Rating Scale, DS = Depression subscale of the Depression and Somatic Symptoms Scale (DSSS), SS = Somatic subscale of the DSSS, HADS-D = Depression subscale of the Hospital Anxiety and Depression Scale (HADS), HADS-A = Anxiety subscale of the HADS
*p < 0.05
** p < 0.01
a The no migraine subgroup was used as a reference.
b Patients without migraine at baseline were categorized as the no migraine group. Patients with migraine diagnosed at baseline and with no headache or mild headache at follow-up were categorized as the inactive migraine group. Patients with migraine diagnosed at baseline and with moderate or severe headache at follow-up were categorized as the active migraine group.
c Subjects with pharmacotherapy in the index follow-up month were categorized as the treated group and those without pharmacotherapy were categorized as the undertreated group.
d The estimate difference was calculated by general linear models and represented the differences in scores between two groups after controlling for demographic variables.