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IC50 values for three P2-family receptor antagonists and apyrase in the presence and absence of thrombin generation capability (n=4 different donors, p>0.39 between CTI only and CTI PPACK)
| CTI only | CTI and PPACK | |
|---|---|---|
| P2Y1 (MRS 2179) [μM] | 0.171 ± 0.093 | 0.227 ± 0.098 |
| P2Y12 (2-MeSAMP) [μM] | 2.619 ± 0.994 | 2.497 ± 0.700 |
| P2X1 (NF 449) [μM] | NA | NA |
| Apyrase (U mL−1) | NA | NA |
