Table 2.

Types of Cell Foci in CMV/Cux-1 Transgenic and Non-transgenic Livers

	Type	8 months	10 months	14 months
CMV/Cux-1 transgenic
Female
	Inflammation (non-suppurative)	4 (6)	3 (5)	3 (3)
	Mixed cell foci	0 (6)	3 (5)	2 (3)
	Oval cell hyperplasia	0 (6)	0 (5)	1 (3)
	Hepatocellular carcinoma	0 (6)	0 (5)	1 (3)
Male
	Inflammation (non-suppurative)	3 (4)	4 (4)	3 (3)
	Mixed cell foci	1 (4)	4 (4)	3 (3)
	Oval cell hyperplasia	0 (4)	0 (4)	1 (3)
	Hepatocellular carcinoma	0 (4)	1 (4)	2 (3)
Non-transgenic
Female
	Inflammation (non-suppurative)	0 (5)	1 (6)	0 (3)
	Mixed cell foci	0 (5)	1 (6)	0 (3)
	Oval cell hyperplasia	0 (5)	1 (6)	0 (3)
	Hepatocellular carcinoma	0 (5)	1 (6)	0 (3)
Male
	Inflammation (non-suppurative)	0 (3)	1 (4)	0 (3)
	Mixed cell foci	0 (3)	1 (4)	0 (3)
	Oval cell hyperplasia	0 (3)	0 (4)	0 (3)
	Hepatocellular carcinoma	0 (3)	1 (4)	0 (3)

Summarized numbers of animals exhibiting preneoplastic lesions and hepatocellular carcinoma in H&E sections of the liver in CMV/Cux-1 transgenic and non-transgenic mice 8, 10, and 14 months after birth. The total number of animals is listed in parentheses.