Table 4. Epitopes that induce IFNγ production from human CD8+ T cells.
PMID | Epitope | Position | Protein | Role/Site | Virus | MHC Allele |
---|---|---|---|---|---|---|
15269378 | AELDRTEEY | 64–72 | M | VA/CP | HRSV | HLA-B44 |
15269378 | RLPADVLKK | 151–159 | M | VA/CP | HRSV | HLA-A3 |
15269378 | IPYSGLLLV | 195–203 | M | VA/CP | HRSV | HLA-B51 |
15269378 | YLEKESIYY | 229–237 | M | VA/CP | HRSV | HLA-A1 |
15755607 | FVPCSICSNNPTCWAICKRIP | 170–190 | G | HBD | HRSV A2 | HLA-Class I |
15269378 | LAKAVIHTI | 41–49 | NS1 | Inh IFN/CP | HRSV | HLA-B51 |
11024156 | RARRELPRF# | 106–114 | F2 | EC | HRSV A2 | HLA-B57 |
12667209 | RELPRFMNYT | 109–118 | F2 | EC | HRSV | HLA-A1 |
11024156 | IAVGLLLYCKA*# | 542–552 | F1 | TM/CP | HRSV A2 | HLA-Cw12 |
17931110 | QLLSSSKYT | 16–24 | NP | RB/CP | HRSV Long | HLA-A*02:01 |
12805430 | KLCGMLLITEDANH | 46–59 | NP | RB/CP | HRSV A2 | HLA-Class I |
17931110 | KMLKEMGEV | 137–145 | NP | RB/CP | HRSV Long | HLA-A*02:01 |
12805430 | STRGGSRVEGIFAG | 232–245 | NP | RB/CP | HRSV A2 | HLA-Class I |
12805430 | AYGAGQVMLRWGVL | 250–263 | NP | RB/CP | HRSV A2 | HLA-Class I |
12805430 | AGQVMLRWGVLAKS | 253–266 | NP | RB/CP | HRSV A2 | HLA-Class I |
12805430 | VMLRWGVLAKSVKN | 256–269 | NP | RB/CP | HRSV A2 | HLA-Class I |
12805430 | AGFYHILNNPKASL | 298–311 | NP | RB/CP | HRSV A2 | HLA-Class I |
17931110 | ILNNPKASL | 303–311 | NP | RB/CP | HRSV Long | HLA-A*02:01 |
12667209 | NPKASLLSL | 306–314 | NP | RB/CP | HRSV | HLA-B7 |
Role/Site abbreviations are included to indicate the role of the protein antigen in viral pathogenesis. VA: viral assembly; CP: cytoplasm; TM: transmembrane; EC: extracellular; HBD: heparin binding domain 184–198; RB: RNA binding; Inh IFN; inhibits IFN-mediated antiviral response; SS: signal sequence/N-terminus.