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. 2015 May 22;10(5):e0127108. doi: 10.1371/journal.pone.0127108

Table 4. Epitopes that induce IFNγ production from human CD8+ T cells.

PMID Epitope Position Protein Role/Site Virus MHC Allele
15269378 AELDRTEEY 64–72 M VA/CP HRSV HLA-B44
15269378 RLPADVLKK 151–159 M VA/CP HRSV HLA-A3
15269378 IPYSGLLLV 195–203 M VA/CP HRSV HLA-B51
15269378 YLEKESIYY 229–237 M VA/CP HRSV HLA-A1
15755607 FVPCSICSNNPTCWAICKRIP 170–190 G HBD HRSV A2 HLA-Class I
15269378 LAKAVIHTI 41–49 NS1 Inh IFN/CP HRSV HLA-B51
11024156 RARRELPRF# 106–114 F2 EC HRSV A2 HLA-B57
12667209 RELPRFMNYT 109–118 F2 EC HRSV HLA-A1
11024156 IAVGLLLYCKA*# 542–552 F1 TM/CP HRSV A2 HLA-Cw12
17931110 QLLSSSKYT 16–24 NP RB/CP HRSV Long HLA-A*02:01
12805430 KLCGMLLITEDANH 46–59 NP RB/CP HRSV A2 HLA-Class I
17931110 KMLKEMGEV 137–145 NP RB/CP HRSV Long HLA-A*02:01
12805430 STRGGSRVEGIFAG 232–245 NP RB/CP HRSV A2 HLA-Class I
12805430 AYGAGQVMLRWGVL 250–263 NP RB/CP HRSV A2 HLA-Class I
12805430 AGQVMLRWGVLAKS 253–266 NP RB/CP HRSV A2 HLA-Class I
12805430 VMLRWGVLAKSVKN 256–269 NP RB/CP HRSV A2 HLA-Class I
12805430 AGFYHILNNPKASL 298–311 NP RB/CP HRSV A2 HLA-Class I
17931110 ILNNPKASL 303–311 NP RB/CP HRSV Long HLA-A*02:01
12667209 NPKASLLSL 306–314 NP RB/CP HRSV HLA-B7

Role/Site abbreviations are included to indicate the role of the protein antigen in viral pathogenesis. VA: viral assembly; CP: cytoplasm; TM: transmembrane; EC: extracellular; HBD: heparin binding domain 184–198; RB: RNA binding; Inh IFN; inhibits IFN-mediated antiviral response; SS: signal sequence/N-terminus.