Table 1. MLST profile and epidemiological characteristics of 33 representative strains (panel A) of all C. abortus genotypes determined by MLVA and characterized as MTs (MT1 to MT7).
MLVA Type | Type-strain for MLVA | Host | Clinical origin | Country | MLST alleles | MLST Type | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
gatA | oppA | hflX | gidA | enoA | hemN | fumC | ||||||
MT1 | C9/98 | sheep | abortion | De | 5 | 8 | 6 | 8 | 8 | 4 | 5 | ST19 |
MT2 | Kra | goat | abortion | De | 5 | 8 | 6 | 8 | 8 | 4 | 18 | ST29 |
Z178/02* | sheep | abortion | De | 18 | 8 | 6 | 8 | 8 | 14 | 5 | ST25 | |
AB1 | sheep | abortion | Fr | 18 | 8 | 6 | 8 | 8 | 14 | 5 | ST25 | |
AB4 | sheep | abortion | Fr | 18 | 8 | 6 | 8 | 8 | 14 | 5 | ST25 | |
AB7 | sheep | abortion | Fr | 18 | 8 | 6 | 8 | 8 | 14 | 5 | ST25 | |
AB8 | sheep | abortion | Fr | 18 | 8 | 6 | 8 | 8 | 14 | 5 | ST25 | |
AB15* | sheep | abortion | Fr | 18 | 8 | 6 | 8 | 8 | 14 | 5 | ST25 | |
AB16 | sheep | abortion | Fr | 18 | 8 | 6 | 8 | 8 | 14 | 5 | ST25 | |
VB1 | sheep | epididymitis | Fr | 18 | 8 | 6 | 8 | 8 | 14 | 5 | ST25 | |
OC1 | sheep | conjunctivitis | Fr | 18 | 8 | 6 | 8 | 8 | 14 | 5 | ST25 | |
1B | - | AB7-mutant | Fr | 18 | 8 | 6 | 8 | 8 | 14 | 5 | ST25 | |
1H | - | AB7-mutant | Fr | 18 | 8 | 6 | 8 | 8 | 14 | 5 | ST25 | |
AB13 | sheep | abortion | Fr | 5 | 8 | 6 | 8 | 8 | 14 | 5 | ST86 | |
AV1 | cattle | abortion | Fr | 5 | 8 | 6 | 8 | 8 | 14 | 5 | ST86 | |
AC1 | goat | abortion | Fr | 5 | 8 | 6 | 8 | 8 | 14 | 5 | ST86 | |
60172 | goat | abortion | It | 5 | 8 | 6 | 8 | 8 | 14 | 5 | ST86 | |
38552 | sheep | abortion | It | 5 | 8 | 6 | 8 | 8 | 14 | 5 | ST86 | |
Krauss-15 | goat | abortion | Tu | 5 | 8 | 6 | 8 | 8 | 4 | 18 | ST29 | |
FAG | goat | abortion | Gr | 5 | 8 | 6 | 8 | 8 | 4 | 5 | ST19 | |
VPG | goat | abortion | Gr | 5 | 8 | 6 | 8 | 8 | 4 | 5 | ST19 | |
MT3 | 71 | sheep | intestinal | Gr | 5 | 8 | 6 | 8 | 8 | 4 | 5 | ST19 |
B577 | sheep | abortion | USA | 5 | 8 | 6 | 8 | 8 | 4 | 5 | ST19 | |
Mo907 | sheep | intestinal | USA | 5 | 8 | 6 | 8 | 8 | 4 | 5 | ST19 | |
Z1215/86 | cattle | abortion | De | 5 | 8 | 6 | 8 | 8 | 4 | 5 | ST19 | |
MT4 | FAS | sheep | abortion | Gr | 5 | 8 | 6 | 8 | 8 | 4 | 5 | ST19 |
4PV | goat | abortion | It | 5 | 8 | 6 | 8 | 8 | 4 | 5 | ST19 | |
BAF | cattle | abortion | UK | 5 | 8 | 6 | 8 | 8 | 4 | 5 | ST19 | |
MT5 | A22 | sheep | abortion | UK | 5 | 8 | 6 | 8 | 8 | 4 | 5 | ST19 |
S26/3 | sheep | abortion | UK | 5 | 8 | 6 | 8 | 8 | 4 | 5 | ST19 | |
MT6 | LLG | goat | abortion | Gr | 13 | 18 | 6 | 19 | 16 | 4 | 17 | ST30 |
POS | sheep | abortion | Gr | 13 | 18 | 6 | 19 | 16 | 4 | 17 | ST30 | |
MT7 | CY71 | sheep | abortion | Cy | 5 | 8 | 6 | 8 | 8 | 4 | 18 | ST29 |
* The Z178/02 and AB15 strains exhibited the 1B-vaccine-type profile; Z178/02 was recovered from a diseased animal in a vaccinated sheep flock while the AB15 strain from an unvaccinated ewe which had extensive contact with a vaccinated herd at the INRA facility in Nouzilly, in 1986, during the original vaccine trials.
The MLVA and MLST types (MTs and STs, respectively) as well as the most diverse MLST loci are indicated in bold. Country abbreviations: De, Germany; Fr, France; Gr, Greece; It, Italy; Tu, Tunisia; UK, United Kingdom; USA, United States of America; Cy, Cyprus.