Skip to main content
. Author manuscript; available in PMC: 2015 Nov 21.
Published in final edited form as: Nature. 2015 Apr 1;521(7552):352–356. doi: 10.1038/nature14274

Figure 2. A surface marker screen identifies an early CD73high CD49dhigh reprogramming intermediate.

Figure 2

a–c, 96 well reprogramming assays on days 3, 6 and 9. 20 cells/well sorted at days 3, 6 and 9. Sox2-EGFP+ colonies were assayed on day 24. Asterisks indicate two-sided t-test P-value<0.05. d, Plating efficiencies for GFP expressing MEFs sorted on day 6 for CD73high or CD49dhigh (assayed 24 hours post-sort). e, Single cell reprogramming efficiencies for day 6 CD73high or CD49dhigh fractions. f, Reprogramming efficiencies (e) adjusted for plating efficiencies (d). Error bars represent standard deviation. n=3 independent experiments for all assays.