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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2015 Apr 23;35(6):1498–1506. doi: 10.1161/ATVBAHA.114.305139

Figure 1. Adipose depot comparison of insulin mediated eNOS activation in obese and non-obese subjects.

Figure 1

A) Insulin significantly increased eNOS phosphorylation at serine 1177 in subcutaneous fat (n=8, p<0.05) but had no effect in visceral fat (n=11, p=0.76) in obese subjects. Representative adipose tissue western blots with and without insulin stimulation quantified for phosphorylated eNOS at serine1177, total eNOS, and GAPDH are displayed. B) Insulin significantly induced p-eNOS in both the subcutaneous and visceral depots in non-obese subjects (n=7, p<0.05). Data are presented as arbitrary units (au), indexed to 1 as the basal condition. Data presented as mean ± SEM. GAPDH= control band.