Table 2.

General health at 4- and 8-week time-points

Groups	Blood glucose* (mg/dl)	Age at surgery (days)	Weight at surgery (g)	Weight at death (g)	Weight change (g)
Saline (n = 5)
4 weeks	444 ± 40	182 ± 15	408 ± 36	404 ± 28	−4 ± 17
8 weeks	421 ± 44	184 ± 11	369 ± 30	401 ± 30	33 ± 24
Buffer + HA/TCP (n = 6)
4 weeks	493 ± 22	187 ± 12	398 ± 40	385 ± 45	−13 ± 43
8 weeks	433 ± 14	175 ± 20	394 ± 33	404 ± 35	10 ± 16
Low-dose rhBMP-2 + HA/TCP (n = 5)
4 weeks	478 ± 38	174 ± 10	401 ± 15	407 ± 18	6 ± 7
8 weeks	440 ± 37	161 ± 8	383 ± 60	383 ± 60	2 ± 17
High-dose rhBMP-2+ HA/TCP (n = 6)
4 weeks	474 ± 44	176 ± 13	404 ± 27	387 ± 32	−16 ± 22
8 weeks	430 ± 27	177 ± 13	425 ± 23	416 ± 11	−8 ± 18

The data represent average values ± standard deviation

* Blood glucose data represents mean data from animals in each treatment group resulting from measurements taken from blood drawn two or three times per week from each animal from onset of T1DM up to death