Table 3.
Groups | Bone mineral density* | p value |
---|---|---|
Saline | ||
4 weeks | 0.951 ± 0.0179 | – |
8 weeks | 1.01 ± 0.852 | – |
Buffer + HA/TCP | ||
4 weeks | 1.43 ± 0.116 | 0.0001 |
8 weeks | 1.15 ± 0.301 | 0.72 |
Low-dose rhBMP-2 + HA/TCP | ||
4 weeks | 1.50 ± 0.0101 | 0.007 |
8 weeks | 1.06 ± 0.0223 | 0.90 |
High-dose rhBMP-2 + HA/TCP | ||
4 weeks | 1.59 ± 0.217 | 0.002 |
8 weeks | 1.37 ± 0.271 | 0.03 |
* Values represent ratio of BMD on operative side to that on contralateral non-operative side (mean ± standard deviation)
p values represent comparison to control group. Bold indicates statistical significance