Table 3.
Total [n (%)] | ||
---|---|---|
No. of patients | N = 31 (100) | |
CTC grade | Grade 1–2 | Grade 3–4 |
Adverse event | ||
Mucositisa | 18 (58) | 1 (3) |
Fatigue | 17 (55) | |
Hand-foot syndrome | 9 (29) | 5 (16) |
Diarrhea | 13 (42) | 2 (6) |
Nausea | 16 (52) | |
Skinb | 20 (65) | 1 (3) |
Anorexia | 8 (26) | |
Vomiting | 12 (39) | 1 (3) |
Neuropathy | 7 (23) | |
Constipation | 4 (13) | |
Ankle edema | 5 (16) | |
Epistaxis | 4 (13) | |
Infection | 3 (10) | |
Hematology | ||
Anemia | 25 (81) | 1 (3) |
Thrombocytopenia | 14 (45) | 2 (6) |
Neutropenia | 12 (39) | |
Clinical chemistry | ||
Hyperglycemiac | 13 (42) | 14 (45) |
AP | 19 (61) | 2 (6) |
ASAT | 11 (35) | |
ALAT | 12 (39) | |
Hypokalemia | 10 (32) | 5 (16) |
Hyponatremia | 7 (23) | |
Hypertriglyceridemia | 7 (23) | |
GGT | 13 (42) | 9 (29) |
Bilirubin | 4 (13) | 1 (3) |
Hypercholesteremia | 3 (10) |
GGT gamma-glutamyltransferase, ASAT aspartate aminotransferase, ALAT alanine aminotransferase, AP alkaline phosphatase
aMucositis including aphthous ulcers and stomatitis
bSkin toxicity includes rash, itching, color and nail changes
cNon-fasting glucose