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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Infect Dis Clin North Am. 2015 Jun;29(2):341–355. doi: 10.1016/j.idc.2015.02.007

Table 4.

Recommended antibiotic treatment for human granulocytic anaplasmosis.11,12,65,66

Antibiotic drug Patient age (years) Antibiotic dose Duration (days)
Doxycycline hyclate ≤ 8 2.2 mg/kg 2 times daily IVa or POb 4 - 5c
> 8 100 mg 2 times daily IV or PO 10 - 14d

Tetracycline HCl > 8 500 mg 4 times daily PO 10 - 14

Rifampin Pediatrice 20 mg/kg/d (max. 600 mg) in 2 divided doses PO 5 - 7f
Adultg 300 mg 2 times daily PO 5 - 7
a

Intravenous administration;

b

Oral administration,

c

Until fever has resolved and three additional days;

d

14 days recommended if suspected co-incubating B. burgdorferi infection;

e

Individuals aged 16 years or less;

f

Short duration since therapy not directed towards co-incubating B. burgdorferi infection;

g

Individuals aged 18 years or older.