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. Author manuscript; available in PMC: 2015 May 23.
Published in final edited form as: Biochemistry. 2015 Feb 6;54(6):1307–1313. doi: 10.1021/bi5012833

Figure 1.

Figure 1

Titration curves (lines) fitted to simulation data (points) with the Hill equation [Eq. (8)]. The upper panel represents the apo enzyme and the lower panel represents the cCMP-bound enzyme. The Hill coefficients for His119, His12 and Lys41 are 0.94, 0.94, 0.98 for the apo enzyme and 1.04, 1.09, 1.10 for the cCMP-bound enzyme, respectively.