Table 1. Study population.
n | 37 |
Age (years) | Median: 6 years (range: 3 days-17 years, IQR: 264 days-12 years) |
Female sex % (n) | 38% (14) |
Race % (n) | |
White | 68% (25) |
Black | 27% (10) |
Asian | 3% (1) |
Other | 3% (1) |
Weight (kg) | Median: 18.7 kg (range: 2.2-90, IQR: 7.7-47.4) |
Height (cm) | 112 cm (range: 47-182, IQR: 66-157) |
Diagnosis | |
Myocarditis | 38% (14) |
Congenital heart disease* | 27% (10) |
Dilated cardiomyopathy | 11% (4) |
Status post heart transplant | 11% (4) |
Hypertrophic cardiomyopathy | 3% (1) |
Restrictive cardiomyopathy | 3% (1) |
Other** | 8% (3) |
Indication for mechanical support | |
Elective or semi-elective | 35% (13) |
Following cardiac arrest | 62% (23) |
Failure to separate from CPB | 3% (1) |
Time on ECMO prior to ASD procedure | Median: 0 (Range: 0-2, IQR: 0-1) |
Indication for creation of atrial communication | |
Clinical suspicion of imminent LA hypertension | 32% (12) |
Evidence of LA hypertension on TTE | 30% (11) |
Pulmonary edema | 22% (8) |
Pulmonary hemorrhage | 14% (5) |
Elevated LA pressure prior to ECMO | 3% (1) |
Total duration of mechanical support (days) | Median: 7 (Range: 2-123, IQR: 5-10) |
Diagnoses include congenital mitral stenosis with mechanical prosthesis (n=2) and transposition of the great arteries after arterial switch operation (n=2), as well as anomalous left coronary from the pulmonary artery with bypass graft, bicuspid aortic valve with aortic insufficiency, critical coarctation of the aorta, tetralogy of Fallot, tetralogy of Fallot pulmonary atresia, and incomplete atrioventricular canal with left atrioventricular valve regurgitation
Includes multi-organ system failure due to hemophagocytic lymphohistiocytosis, myocardial infarct of unknown etiology, and transient cardiac dysfunction in a child with very long chain acyl-coenzyme A dehydrogenase deficiency