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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Free Radic Biol Med. 2015 Mar 17;83:252–261. doi: 10.1016/j.freeradbiomed.2015.02.035

Fig 1.

Fig 1

Blood pressure measurement showed that the NOS pathway is a major determinant of T4-induced hemodynamic changes in mice. Representative bar graphs show (A) systolic, (B) diastolic, and (C) mean arterial blood pressure and (D) heart rate in mice. T4, thyroxin; L-NIO, N5-(1-iminoethyl)-l-ornithine dihydrochloride; BPM, beats per minute. Control, n=13; T4, n=12; allopurinol, n=11; apocynin, n=12; L-NIO, n=10; MitoTEMPO, n=12. *Significant change compared with T4 group (one-way ANOVA followed by Dunnett multiple comparisons post hoc test, comparing all groups to T4).