Table 4.
Comparison of changes in the scores of psychological subscales in the two groups
| Before the intervention | 1 month after the intervention | 2 months after the intervention | 3 months after the intervention | P -value | |||||
|---|---|---|---|---|---|---|---|---|---|
| Dimension | Group | Mean + SD (CI 95%) |
Mean + SD (CI 95%) |
Mean + SD (CI 95%) |
Mean + SD (CI 95%) |
CV | Time | Group | Time × group |
| Depression | Melatonin | 9.16±3.69*b,c,d
(8.42-9.90) |
6.40±3.91.a,c,d
(5.61-7.18) |
5.06±3.56a,b,d
(4.35-5.78) |
4.03+3.30a,b,c
(3.37-4.60) |
41.72 | <0.001 | 0.017 | 0.001 |
| Placebo | 9.23+3.65b,c,d (8.51-9.95) |
7.13+3.95a,c,d (6.35-7.91) |
6.22±3.72a,b (5.48-6.95) |
5.83+3.58a,b (5.13-6.54) |
21.81 | ||||
| Anxiety | Melatonin | 9.68+3.88*b,c,d (8.91-10.46) | 7.26+4.03a,c,d (6.45-8.06) | 5.49+3.36a,b,d (4.82-6.16) | 4.56+3.74a,b,c (3.81-5.31) | 41.83 | <0.001 | 0.007 | 0.001 |
| Placebo | 10.13+3.89b,c,d (9.36-10.90) | 7.72+3.82a,d (9.97-8.48) | 7.23+4.17a,d (6.41-8.05) | 6.44+3.83a,b,c (5.68-7.19) | 21.02 | ||||
Values are given as mean± standard deviation. Repeated Measure ANOVA test and then Sidak Post hoc/*: the two groups were similar regarding the subscales of Psychological dimension before the intervention (P>0.05)./ a: significant difference compared to before the intervention/b: significant difference compared to 1 month after the intervention/c: significant difference compared to 2 months after the intervention/d: significant difference compared to 3 months after the intervention