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Diagram of a model for CRMP2 and CRMP4 coordinately regulating growth cone development and axon elongation via cytoskeleton dynamics. The schematic model shows that CRMP2 and CRMP4 may form complexes (homo- or heterotetramers) bridging microtubules and actin to mediate cytoskeleton dynamics, thus regulating growth cone development and axon elongation.
