Fig. 5.
Schematic diagram of the ex vivo/in vivo CCD-based redox imager. CCD model: COHU 4912-5010. Excitation filters: 365BP20 for NADH and 436DF10 for Fp; Emission filters: 450DF10 for NADH and 546DF10 for Fp. The cold chamber of liquid nitrogen is only necessary for ex vivo imaging to hold snap-frozen samples. It is replaced with a supporting frame on which a small animal lies for in vivo imaging. Grinder is not shown. Reproduced from Xu et al.42 with permission from SPIE.