Table 2.
Prior immunosuppressive therapy and EBV/CMV status of 10 patients with Primary CNS Post-Transplant Lymphoproliferative Disorder.
| N | |
|---|---|
| Prior rejection episodes of organ allograft | 9 (90%) |
| Steroid-refractory | 2 (20%) |
|
| |
| Prior exposure to immunosuppressive agents for treatment of organ rejection: | |
| OKT3 | 0 |
| ATG | 4† |
|
| |
| Immunosuppressive agents at time of PTLD diagnosis: | |
| Cyclosporine | 2 |
| Tacrolimus | 3 |
| Mycophenolate | 10 |
| Prednisone | 10 |
One patient had received ATG prophylactically as pre-transplant conditioning regimen.
Abbreviations: OKT3 = murine monoclonal antibody targeting CD3. ATG = anti-thymocyte globulin.