Table 3.

Multiple regression analysis for identifying predictors of Mean Change ADC

Model	Variable	Unstandardized coefficients B	Standard error	P
Left Internal Capsule
1	ADC Scan 1†	−0.43	0.17	0.03†
	Age	−1.36	1.35	0.33
2	ADC Scan 1†	−0.32	0.12	0.02†
	Gender	−23.3	8.29	0.01†
3	ADC Scan 1†	−0.40	0.12	0.006†
	Epilepsy†	22.5	8.74	0.02†
4	ADC Scan 1†	−0.40	0.15	0.02†
	ASD	13.3	11.5	0.27
Right Internal Capsule
1	ADC Scan 1†	−0.36	0.13	0.02†
	Age	0.21	1.27	0.87
2	ADC Scan 1†	−0.37	0.94	0.001‡
	Gender	13.1	8.14	0.13
3	ADC Scan 1†	−0.40	0.11	0.003†
	Epilepsy	6.23	9.56	0.53
4	ADC Scan 1†	−0.37	0.12	0.006†
	ASD	0.55	10.69	0.96
Left Cingulum
1	ADC Scan 1	−0.03	0.16	0.88
	Age	−0.05	1.17	0.97
2	ADC Scan 1	−0.06	0.10	0.56
	Gender†	−23.8	6.44	0.002†
3	ADC Scan 1	−0.09	0.15	0.54
	Epilepsy	10.7	9.51	0.28
4	ADC Scan 1	−0.20	0.14	0.87
	ASD	0.59	9.91	0.95
Right Cingulum
1	ADC Scan 1	−0.13	0.13	0.36
	Age	1.45	1.27	0.27
2	ADC Scan 1	−0.21	0.11	0.07
	Gender	−20.1	9.02	0.04
3	ADC Scan 1	−0.23	0.13	0.08
	Epilepsy	10.2	10.6	0.35
4	ADC Scan 1	−0.22	0.127	0.11
	ASD	6.34	11.64	0.60
Corpus Callosum
1	ADC Scan 1†	−0.24	0.111	0.05†
	Age	2.42	1.88	0.22
2	ADC Scan 1†	−0.32	0.096	0.005†
	Gender	−31.8	14.64	0.05†
3	ADC Scan 1†	−0.32	0.12	0.02†
	Epilepsy	12.0	18.13	0.52
4	ADC Scan 1	−0.26	0.125	0.05†
	ASD	−9.32	20.48	0.66

Abbreviations: ASD, autism spectrum disorder; ADC (mm²/sec), apparent diffusion coefficient ; Age (years)

Reference: Gender, 0= male; Epilepsy, 0= no epilepsy; ASD, 0=no ASD

^†p≤0.05;

^‡p≤0.001.