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. Author manuscript; available in PMC: 2016 Jun 4.
Published in final edited form as: FEBS Lett. 2015 May 8;589(13):1491–1497. doi: 10.1016/j.febslet.2015.04.047

Figure 1. The effect of synergist ablation on YAP, Akt and c-Myc, and mTORC1 signaling.

Figure 1

Plantaris muscles were subjected to synergist ablation (SA) and then collected either immediately (0 day) or up 14 days after the onset of SA. (A) The muscles were subjected to Western blot analysis with the indicated antibodies and then the Western blot membranes were stained with Coomassie blue to verify equal loading of protein in all lanes. (B) The mean time course data for the phosphorylated to total ratio (P/T) of p70S6k1, and the amounts of phosphorylated Akt [P-Akt(T308)] and YAP. (C) Correlation between the SA-induced changes in YAP and P-Akt(T308). All values are expressed as a percentage of the mean value obtained in the control (0 day) samples and are reported as the mean + SEM, n = 3-8 / group. * Significantly different from 0 day, P ≤ 0.05.