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. 2015 May 19;84(20):2092–2093. doi: 10.1212/WNL.0000000000001581

Figure. Clinical features in 2 brothers with adenosine deaminase 2 deficiency.

Figure

3T T1-weighted (A) and fluid-attenuated inversion recovery (B) MRI of patient 1, performed at age 21 years, show thalamic infarction (arrows). (C) 1.5T T2-weighted MRI of patient 2 performed at age 7 years with arrows indicating left and right lacunar pontine infarcts. (D) Bilateral erythematous swelling of both feet at age 21 years. (E–G) Hematoxylin & eosin stain of skin biopsy of foot with intact epidermis (E, white arrow) and including subcutaneous fat (E, black arrow) reveals necrotizing vasculitis with necrosis (arrow in F) and multiple thrombi and fibrin (arrow in G).