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Citrulline flux (A) and de novo arginine synthesis (B) of BL6 and ICR mice fed arginine-free or arginine-sufficient diets (8-g/kg diet). BL6 mice had a reduced citrulline flux and de novo arginine synthesis than ICR mice (P < 0.002). Diet had no effect on these variables. Bars are means ± SEs, n = 10. *Different from BL6 mice fed the same diet, P < 0.01. BL6, C57BL/6; ICR, Institute of Cancer Research.
