TABLE 1.
AA (n = 62) | AG (n = 268) | GG (n = 413) | P2 | |
Age, y | 47.9 ± 8.3 | 50.5 ± 9.1 | 51.9 ± 9.4 | 0.06 |
Female | 21 (33.9) | 103 (38.4) | 166 (40.2) | 0.62 |
Dietary fat group | 0.83 | |||
Low fat | 30 (8.1) | 138 (37.1) | 204 (54.8) | |
High fat | 32 (8.6) | 130 (35.0) | 209 (56.3) | |
Race or ethnic group | <0.0001 | |||
White | 31 (5.2) | 198 (33.3) | 366 (61.5) | |
Black | 27 (24.1) | 53 (47.3) | 32 (28.6) | |
Hispanic | 3 (12.0) | 13 (52.0) | 9 (36.0) | |
Asian or other | 1 (9.0) | 4 (36.4) | 6 (54.6) | |
Height, cm | 167 ± 8.5 | 169 ± 9.2 | 169 ± 8.5 | 0.09 |
Weight, kg | 91.8 ± 14.2 | 93.5 ± 15.2 | 93.3 ± 16.0 | 0.22 |
Waist circumference, cm | 103 ± 12.5 | 103 ± 12.9 | 104 ± 13.3 | 0.75 |
BMI, kg/m2 | 33.0 ± 3.8 | 32.7 ± 3.8 | 32.6 ± 3.9 | 0.75 |
Blood pressure, mm Hg | ||||
Systolic | 122 ± 16 | 120 ± 13 | 119 ± 13 | 0.05 |
Diastolic | 77 ± 11 | 76 ± 9 | 75 ± 9 | 0.20 |
Fasting serum glucose, mg/dL | 93 ± 16 | 91 ± 11 | 92 ± 12 | 0.88 |
Fasting serum lipid profile, mg/dL | ||||
TGs | 98.5 [70.0–168] | 121 [80.0–165] | 124 [90.0–193] | 0.17 |
TC | 205 ± 41.3 | 201 ± 37.1 | 203 ± 36.1 | 0.47 |
HDL cholesterol | 51.0 ± 14.3 | 49.6 ± 15.6 | 47.9 ± 13.0 | 0.002 |
LDL cholesterol | 129 ± 34.2 | 125 ± 31.3 | 126 ± 32.2 | 0.99 |
Dietary intake per day | ||||
Carbohydrate, % of energy | 45.9 ± 7.5 | 45.2 ± 8.0 | 44.1 ± 7.4 | 0.28 |
Fat, % of energy | 35.8 ± 6.9 | 37.0 ± 6.3 | 37.1 ± 5.7 | 0.48 |
Protein, % of energy | 18.3 ± 3.2 | 17.7 ± 3.3 | 18.4 ± 3.4 | 0.17 |
Energy, kcal | 1881 ± 572 | 2036 ± 539 | 1936 ± 569 | 0.33 |
Urinary nitrogen, g/d | 11.3 ± 4.6 | 12.2 ± 4.5 | 12.4 ± 4.3 | 0.54 |
Respiratory quotient | 0.84 ± 0.05 | 0.84 ± 0.04 | 0.84 ± 0.04 | 0.72 |
Values are means ± SDs, medians [IQRs], or n (%). LIPC, hepatic lipase gene; TC, total cholesterol.
P values were calculated by χ2 test for categorical variables and ANCOVA for continuous variables after adjusting for age, sex, and ethnicity.