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. 2015 May 21;5(5):e008026. doi: 10.1136/bmjopen-2015-008026

Table 5.

Adjusted HRs, based on a Cox proportional hazards analysis of factors associated with incident eGFR<60 mL/min/1.73 m2

p Value HR 95% CI
Age (years) 0.019 1.030 1.005 1.056
Baseline eGFR (mL/min/1.73 m2) <0.001 0.957 0.944 0.971
Body mass index (kg/m2) 0.777 1.006 0.967 1.045
Women (%) 0.994 1.001 0.711 1.409
Permanent AF (%) 0.395 0.862 0.611 1.214
Ankle-Brachial Index ≤0.90 (%) 0.005 1.851 1.205 2.845
Arterial hypertension (%) 0.052 1.860 0.994 3.481
Diabetes (%) 0.151 0.713 0.449 1.132
Heart failure (%) 0.841 1.055 0.627 1.774
History of stroke/TIA (%) 0.867 1.046 0.619 1.767
History of MI/CHD (%) 0.172 0.725 0.457 1.150
Antiplatelet (%) 0.518 0.864 0.555 1.346
ACE inhibitors/ARBs (%) 0.442 0.842 0.543 1.306
β blockers (%) 0.788 1.052 0.728 1.521
Calcium channel antagonists (%) 0.029 0.640 0.429 0.954
Statins (%) 0.434 1.148 0.812 1.622

ACE, angiotensin converting enzyme; AF, atrial fibrillation; ARBs, angiotensin receptor blockers; CHD, coronary heart disease; eGFR, estimated glomerular filtration rate; MI, myocardial infarction; TIA, transient ischaemic attack.