Figure 1.

Experimental design to describe periparturient nematode egg rise (PPER) of ewes naturally infected with gastrointestinal nematodes and to measure the efficacy and persistency of peripartum strategic treatment with moxidectin (Mox) either at the onset of late pregnancy (TT₁) or at the end of immediate peripartum (TT₂) period under tropical Andes high altitude conditions. Parasitological and clinical evaluations included FEC by McMaster test, anemia detection by FAMACHA© system, diarrhea assessment by Dag scoring, body weight, and body condition assessment. Fecal egg count reduction (FECR) was employed to test posttreatment moxidectin efficacy 15 days after treatment (PE_MoxT1 and PE_MoxT2), the prevention of PPER at late postpartum (PPER_Pre) period, and preweaning persistency (PW_Per⁡). Ewes in control group (C) and offspring of all ewes were untreated against gastrointestinal nematodes. D: dry ewes; M: mating; MP: midpregnancy; LP: late pregnancy; Ipr: immediate postpartum; Epp: early postpartum; Ipp: intermediate postpartum; LPp: late postpartum; and PW: preweaning.