FIG 7.
Infection of A(H7N9) virus results in both apoptosis and necrosis in human bronchial epithelial cells. Calu-3 cells grown on transwells were infected apically with viruses at an MOI of 1. At 40 h p.i., cell lysates and supernatants were analyzed using a Cell Death Detection ELISAPLUS kit for apoptosis and necrosis, respectively. Values represent the mean OD values of three independent experiments plus standard deviations. An asterisk indicates that Anhui/1 virus induced a significantly higher level of necrosis than did the other tested viruses (P < 0.05).