Wild-type and hDAF transgenic mice are equally susceptible to intraperitoneal infection by a DAF-binding virus isolate, CVB3 H3-RD. (A) Wild-type C57BL/6 mice were injected intraperitoneally with 105 PFU of CVB3 Nancy, RD, H3, and H3-RD, and virus titers in tissues were measured after 2 days. Titers obtained in individual animals are shown, with mean titers indicated as bars. (B) Wild-type (WT) and hDAF transgenic mice were injected intraperitoneally with 105 PFU of CVB3 H3-RD, and virus titers in tissues were measured as described above. P, pancreas; S, spleen; L, liver; H, heart.