FIG 2.
SIVmac239 restriction by AgmTRIM5α and gorTRIM5α. Flow cytometry analyses for SIV infection in untransduced CD4 T-cell clones and those expressing AgmTRIM5α or gorTRIM5α are presented. Plots of gated cells are shown for CD4 staining on the y axis and SIV Gag staining on the x axis. (A) SIVmac239 restriction in 3 representative clones (clones 34, 2, and 22) at day 5 postinfection. (B) SIVmac239 restriction in the representative clone 128 at days 4, 5, and 6 postinfection. Data presented are representative of three independent trials.