TABLE 1.
Histone acetylation levels for each lysine in primary neuronal cultures expressing isolated viral proteinsa
| Histone | Lysine | BDV P |
BDV N |
||
|---|---|---|---|---|---|
| n | Acetylation level (mean ± SEM) | n | Acetylation level (mean ± SEM) | ||
| H2B | K5 | 7 | 0.63 ± 0.06*** | 3 | 1.02 ± 0.03 |
| K15 | 7 | 0.55 ± 0.08** | 3 | 0.93 ± 0.04 | |
| K20 | 7 | 0.62 ± 0.06** | 5 | 0.97 ± 0.04 | |
| H4 | Pan Ac | 7 | 0.70 ± 0.08** | 4 | 0.97 ± 0.03 |
| K5 | 5 | 0.64 ± 0.07** | 4 | 1.00 ± 0.08 | |
| K8 | 4 | 0.63 ± 0.06** | 2 | 1.00 ± 0.03 | |
| K12 | 4 | 0.94 ± 0.04 | 3 | 1.04 ± 0.04 | |
| K16 | 4 | 0.77 ± 0.06* | 3 | 1.01 ± 0.13 | |
a
Acetylation levels are expressed as variations compared to the mean levels of control cells (uninfected or mock transfected/transduced), which were set to 1. n, number of independent sets of neuronal cultures; Pan Ac, pan-acetylated. *, P≤ 0.05; **, P ≤ 0.01; ***, P ≤ 0.001.