Fig. 5.

Apparent transition rate constants of EXP-2. The apparent voltage-dependent rate constants (per second) for activation, inactivation, recovery from inactivation (deinactivation), and deactivation were calculated as the reciprocal values of the corresponding time constants τ_act, τ_inact, τ_rec, and τ_deact. It is apparent that inactivation and recovery from inactivation is up to ∼100 times faster than activation. Deactivation is very slow and not voltage-dependent between −80 and −120 mV. Open inverted triangles (inactivation) indicate data points obtained with the cut-open oocyte technique; all other data were obtained using the two-electrode voltage clamp on whole oocytes.